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We partner with you on the front line of intensive care, so you can help deliver accurate, effective, and efficient treatment for ICU patients with Acute Kidney Injury and other acute renal conditions.


PRISMAX System CRRT Machine with THERMAX.

What if you could experience the next generation in CRRT?

Now you can.

Building on Baxter’s 20-plus years of critical care expertise, the PRISMAX system is designed to help you optimize therapy delivery and quality of care for critically ill patients with acute kidney injury. With its intuitive interface and smart features like the integrated THERMAX Blood Warmer, auto-effluent drain, and fluid-removal catch-up, the PRISMAX System is designed to maximize simplicity, efficiency and accuracy in CRRT. 

We Support a Range of Therapies


PRISMAFLEX and PRISMAX Systems allow an easy switch between four treatment modalities.


Hospitals that own a PRISMAFLEX System can run TPE without purchasing an additional machine.

Drug Overdose / Poisoning

MARS works with the PRISMAFLEX System to provide liver detoxification for the removal of harmful drugs and poisons in combination with CRRT.

Featured Presentation
Stephanie presentation

CRRT in the Era of Drug Shortages

Stephanie Chamberland, RN explains the differences in compounded bags versus commercially available premixed solutions and what can be done to avoid the issues related to drug shortages.

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The PRISMAFLEX and PRISMAX Systems are intended for:
Continuous Renal Replacement Therapy (CRRT) for patients weighing 20 kilograms or more with acute renal failure and/or fluid overload.

Therapeutic Plasma Exchange (TPE) therapy for patients weighing 20 kilograms or more with diseases where fluid removal of plasma components is indicated.

Rx Only. For safe and proper use of products mentioned herein refer to the appropriate Instructions for Use or Operator's Manual.

PHOXILLUM and PRISMASOL Renal Replacement Solution Indications and Important Risk Information

Indications and Usage 
PRISMASOL and PHOXILLUM solutions are indicated in pediatric and adult patients for use as a replacement solution in Continuous Renal Replacement Therapy (CRRT) to replace plasma volume removed by ultrafiltration and to correct electrolyte and acid-base imbalances. They may also be used in case of drug poisoning when CRRT is used to remove dialyzable substances.

Warnings and Precautions 
Electrolyte and Volume Abnormalities
PHOXILLUM and PRISMASOL solutions can affect electrolytes and volume and may result in hyperkalemia or hyperphosphatemia. Monitor hemodynamic status and fluid inputs and outputs, potassium, phosphorous, calcium, other electrolytes and acid-base balance throughout the procedure. Abnormalities may be corrected by changing the formulation of replacement solution and/or dialysate, supplementation, or adjusting flow rates appropriately. PHOXILLUM replacement solutions contain hydrogen phosphate, a weak acid that may increase the risk of metabolic acidosis.

Blood Glucose Abnormalities
The use of PRISMASOL and PHOXILLUM replacement solutions can affect blood glucose levels resulting in hypo- or hyper-glycemia depending upon the dextrose content of the replacement solution. Monitor blood glucose levels regularly. Patients may require initiation of or modification of antidiabetic therapy or other corrective measures during treatment.

Please see PHOXILLUM and PRISMASOL Solutions full Prescribing Information.

MARS is indicated for the treatment of drug overdose and poisonings. The only requirement is that the drug or chemical be dialyzable (in unbound form) and bound by charcoal and/or ion exchange resins.

MARS is not indicated for the treatment of chronic liver disease conditions or as a bridge to liver transplant. Safety and efficacy has not been demonstrated for those indications in controlled, randomized clinical trials. The effectiveness of the MARS device in patients that are sedated could not be established in clinical studies and therefore cannot be predicted in sedated patients.